The Centre for Gynaecological Cancer Research has been developed to investigate various treatment modalities for the improvement of management of gynaecological cancer.
Developed in 2002, the Centre is comprised of staff from various backgrounds, including medical, nursing and research workers. The mission of the Research Centre is to achieve best practice in health care and improve outcomes in Australia and Internationally through the use of clinical trials research.
The Centre has several major research investigations under trial, most notably the LACE (Laparoscopic Approach to Carcinoma of the Endometrium) and SIS (Skin Incision Study) trials.
LACE (Laparoscopic Approach to Carcinoma of the Endometrium).
Endometrial cancer is the most common gynaecological malignancy in countries of the developed world. In 2000, 1,564 new cases of endometrial cancer were diagnosed in Australia and the incidence is steadily rising.
The LACE Trial is an international multi-centre randomised phase three clinical trial investigating the differences in the quality of life of patients with Stage 1 Endometrial Adenocarcinoma post Total Abdominal Hysterectomy versus Total Laparoscopic Hysterectomy.
For patients with Stage 1 endometrial cancer, removal of the uterus, tubes and ovaries is considered the current standard treatment. Traditionally this surgery is performed via laparotomy in health care facilities throughout the world. More recently, however, advances in laparoscopic techniques have allowed the completion of a hysterectomy to be performed entirely laparoscopically with the aid of the McCartney Tube, which facilitates the removal of the uterus through the vagina.
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