Hypogonadism & infertility – male

ADULT
  • If any of the following are present or suspected, please refer the patient to the emergency department (via ambulance if necessary) or follow local emergency care protocols or seek emergent medical advice if in a remote region.

    Adult conditions

    Pancreatic disease

    • Diabetic ketoacidosis - A
    • Diabetes and severe vomiting -A
    • Acute severe hyperglycaemia
    • Acute severe hypoglycaemia -A
    • Hyperosmolar hyperglycaemic state (HHS) -A
    • Newly diagnosed type 1 diabetes –B (call registrar or consultant on call)
    • Foot ulcer with infection and systemically unwell or febrile -A
    • Invasive infection or rapidly spreading cellulitis of the foot (defined by peripheral redness around the wound >2cm) -A
    • Acute foot ischaemia -A
    • Wet gangrene foot -A

    Urgent cases – (refer to key below)
    A – client to present to emergency department immediately
    B – client to present to diabetes specialist service within 24 hours. If no specialist service is available, present to an emergency department.

    High Risk Foot

    • Foot ulcer with infection and systemically unwell or febrile
    • Invasive infection or rapidly spreading cellulitis (defined by peripheral redness around the wound >2cm)
    • Acute ischaemia
    • Wet gangrene
    • Acute or suspected Charcot

    Thyroid disorders

    • Hyperthyroidism complicated by cardiac, respiratory compromise or other indications of severe illness (fever, vomiting, labile blood pressure, altered mental state)
    • Neutropenic sepsis in patient taking carbimazole or propylthiouracil
    • Hyperthyroidism with hypokalaemia or paralysis
    • Suspected myxoedema coma (altered consciousness, hypothermia, fluid overload, bradycardia, hyponatraemia)
    • Stridor associated with a thyroid mass
    • Possible tracheal or superior vena cava obstruction from retrosternal thyroid enlargement

    Adrenal disease

    • Addisonian crisis
    • Suspected or confirmed acute adrenal insufficiency
    • Phaeochromocytoma in crisis with uncontrolled hypertension

    Pituitary disorders

    • All patients with visual field loss (usually temporal and classically bitemporal superior quadrantinopia/hemianopia)
    • Pituitary tumour with severe headache
    • Pituitary tumour with evidence of symptomatic cortisol insufficiency
    • Hyperprolactinaemia with visual impairment or other neurological signs

    Oligo/amenorrhoea, hirsutism, acne, female infertility

    • Signs in the central nervous system that could indicate a pituitary tumour (visual field defect headaches)

    Calcium, electrolyte and metabolic bone disorders

    • Acutely symptomatic hypocalcaemia (e.g. tetany) with serum calcium <2.0mmol/L
    • Severe symptomatic hypercalcaemia (usually serum calcium > 3.0 mmol/l)
    • Hypernatraemia or hyponatraemia with acute confusion/delirium
    • Suspected or confirmed diabetes insipidus with hypernatraemia

    Paediatric Conditions

    Paediatric diabetes

    • New diagnosis of type 1 diabetes = polyuria and/or polydipsia and random BSL >11.0.
    • Ketoacidosis in a known diabetic with any of the following
      • systemic symptoms (fever, lethargy) or
      • vomiting or
      • inability to eat (even if not vomiting) or
      • abdominal pain or
      • headache

    Growth failure

    • Suspected pituitary mass (visual field loss/CNS signs)
    • Addisonian crisis (including unexplained hyponatraemia & hypoglycaemia)
    • Myxoedema coma
    • New onset diabetes insipidus (including unexplained hypernatraemia)
    • Hypocalcaemia (including acute rickets) with seizures

    • Refer to local Healthpathways or local guidelines
    • Low testosterone levels can be associated with obesity, sleep apnoea, pain killers, alcohol and depression

    *PBS subsidised testosterone treatment must be prescribed initially by an endocrinologist and patients must have two morning testosterone levels < 6 with established pituitary or gonadal disease

Minimum Referral Criteria
Category 1
(appointment within 30 calendar days)
  • Arrested puberty (16 years and over)
  • Suspected hypopituitarism
Category 2
(appointment within 90 calendar days)
  • Delayed puberty (16 years and over)
  • Male infertility
  • Confirmed hypogonadism with two morning testosterone levels under 6
  • Azoospermia
Category 3
(appointment within 365 calendar days)
  • Symptoms of androgen deficiency with testosterone levels over 6*

Please insert the below information and minimum referral criteria into referral

1. Reason for request Indicate on the referral

  • To establish a diagnosis
  • For treatment or intervention
  • For advice and management
  • For specialist to take over management
  • Reassurance for GP/second opinion
  • For a specified test/investigation the GP can't order, or the patient can't afford or access
  • Reassurance for the patient/family
  • For other reason (e.g. rapidly accelerating disease progression)
  • Clinical judgement indicates a referral for specialist review is necessary

2. Essential referral information Referral will be returned without this

  • History
    • age and health
    • reproductive history
    • testicular condition
  • Height, weight, BMI
  • Morning (0700-0900 hours) sample for LH, FSH, total testosterone,
  • SHBG and prolactin
  • Morning (08:00-09:00) Cortisol
  • TSH, T4
  • IGF1
  • If infertility - seminal analysis (≥4 days of abstinence)
    • repeat in 4-6 weeks if abnormal

3. Additional referral information Useful for processing the referral

  • Pituitary investigations if LH, FSH not elevated
  • Bone mineral densitometry
  • History of marijuana use (including partner) or other relevant medications that contribute to infertility e.g. illicit drugs, steroids, chemotherapy – make reference if appropriate

4. Request

  • Patient's Demographic Details

    • Full name (including aliases)
    • Date of birth
    • Residential and postal address
    • Telephone contact number/s – home, mobile and alternative
    • Medicare number (where eligible)
    • Name of the parent or caregiver (if appropriate)
    • Preferred language and interpreter requirements
    • Identifies as Aboriginal and/or Torres Strait Islander

    Referring Practitioner Details

    • Full name
    • Full address
    • Contact details – telephone, fax, email
    • Provider number
    • Date of referral
    • Signature

    Relevant clinical information about the condition

    • Presenting symptoms (evolution and duration)
    • Physical findings
    • Details of previous treatment (including systemic and topical medications prescribed) including the course and outcome of the treatment
    • Body mass index (BMI)
    • Details of any associated medical conditions which may affect the condition or its treatment (e.g. diabetes), noting these must be stable and controlled prior to referral
    • Current medications and dosages
    • Drug allergies
    • Alcohol, tobacco and other drugs use

    Reason for request

    • To establish a diagnosis
    • For treatment or intervention
    • For advice and management
    • For specialist to take over management
    • Reassurance for GP/second opinion
    • For a specified test/investigation the GP can't order, or the patient can't afford or access
    • Reassurance for the patient/family
    • For other reason (e.g. rapidly accelerating disease progression)
    • Clinical judgement indicates a referral for specialist review is necessary

    Clinical modifiers

    • Impact on employment
    • Impact on education
    • Impact on home
    • Impact on activities of daily living
    • Impact on ability to care for others
    • Impact on personal frailty or safety
    • Identifies as Aboriginal and/or Torres Strait Islander

    Other relevant information

    • Willingness to have surgery (where surgery is a likely intervention)
    • Choice to be treated as a public or private patient
    • Compensable status (e.g. DVA, Work Cover, Motor Vehicle Insurance, etc.)
  • If any of the following are present or suspected, please refer the patient to the emergency department (via ambulance if necessary) or follow local emergency care protocols or seek emergent medical advice if in a remote region.

    • Please note that where appropriate and where available, the referral may be streamed to an associated public allied health and/or nursing service. Access to some specific services may include initial assessment and management by associated public allied health and/or nursing, which may either facilitate or negate the need to see the public medical specialist.

    • A change in patient circumstance (such as condition deteriorating, or becoming pregnant) may affect the urgency categorisation and should be communicated as soon as possible.

    • Please indicate in the referral if the patient is unable to access mandatory tests or investigations as they incur a cost or are unavailable locally.

Last updated: 11 June 2021

© State of Queensland (Queensland Health) 2023

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